Senior Director, Clinical Science

Company Overview

Accent Therapeutics is a biopharmaceutical company based in Lexington, MA that is focused on developing first in class and best in class small molecule Inhibitors of RNA modifying enzymes (RMEs) and adjacent pathways to primarily treat cancer. Founded in 2017, named as one of Fortune's Top Ten Workplaces in Healthcare and Biopharma in 2020, and one of Fierce Biotech's Fierce15 in 2020, Accent is building a highly collaborative team of experienced high-caliber drug developers to develop life-changing therapies for patients.

Position Summary

This key individual will report to the Chief Medical Officer, interface directly with multiple early development oncology teams and external investigators/advisors/companies to lead innovation and enable Accent Therapeutics to achieve a higher probability of success in developing novel anti-cancer therapeutics.

Responsibilities

• Provide clinical expertise and leadership to 1-2 clinical development programs
• Conduct clinical studies: collaborate closely with Clinical Operations to manage the CRO vendor to ensure patient appropriateness and evaluate safety data coming from the clinical studies
• Liaise with the Clinical Investigators at the clinical sites to facilitate trial participation and identify issues that arise
• Establish and grow KOL support for the Clinical Development Programs - The clinical scientist will be responsible for evaluating, prioritizing, establishing, and bringing in the results for these collaborations
• Provide strategic guidance for compounds and devise clinical development strategies, assessment of competition, and approval strategy
• Design and draft clinical documents (protocol synopses, protocols, amendments, investigator brochure etc.) in concert with team, translational biology, statistician, clin ops, & regulatory
• Review literature and author clinical abstracts, prepare data for various presentations including presenting at conferences when appropriate
• Enable a focus on the cancer patient

Requirements

• An advanced degree preferred (PhD, PharmD). Individuals without an advanced degree but with significant relevant experience will also be considered
• 5-7+ years of experience working as a clinical scientist in the biotech/pharmaceutical industry
• Industry experience in oncology drug development, clinical trial conduct and safety reporting
• The candidate should have high level of independence, motivation, innovation, and excellent communication skills with team-oriented style to facilitate exchanges within a matrixed environment
• Excellent interpersonal and presentation skills required
• Willing to travel (mostly domestic) occasionally, meet with investigators, attend conferences, participate in advisory boards, including over occasional weekends